Eddie Southern was one of the few track stars in the world who excelled in many different racing events. At the University of Texas, Southern was a member of an 880-yard relay team that set a word record at the 1957 Texas Relays. As the anchor of the mile relay team at the Kansas relays in 1958, Southern became the first person to run the quarter mile in under 45 seconds. Southern also anchored the 440-yard relay team that set two world records in four years. Ironically, the race he prized the most, the Olympic 400-yard hurdles, was the only big race he lost.
A teammate beat Southern with a 50.1-second run that tied the Olympic record Southern had set in the semi- finals. He was inducted into the Texas Sports Hall of Fame in 1969.